Summary
Insertion of a dialysis probe in the cerebral cortex damages the BBB in the surrounding cortex. Extravasation of plasma constituents from the probe site leads to gliosis in the ipsilateral white matter, thalamus and the lateral geniculate body far from the site of the probe.
Résumé
L’insertion d’une sonde de dialyse dans le cortex cérébral provoque une lésion de la BHE dans le tissu cortical environnant. L’extravasation de constituants plasmatiques à partir du site d’implantation entraîne une gliose dans la substance blanche ipsilatérale, le thalamus et le corps géniculé latétal, à distance du site d’implantation.
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References
Benveniste H. (1989) Brain microdialysis. J. Neurochem. 52, 1667–1679.
Westergren 1. Nyström B, Hamberger A, Johansson BB (1995) Intracerebral dialysis and the blood-brain barrier. J. Neurochem. 64: 229–234.
Persson L. (1976) Cellular reactions to small cerebral stab wounds in the rat frontal lobe. An ultrastructural study. Virchows Arch. [B] 22, 21–37.
Persson L., Hansson H.-A., and Sourander P. (19761 Extravasation, spread and cellular uptake of Evans blue-labelled albumin around a reproducible small stab-wound in the rat brain. Acta Neuropathol. (Berl) 34: 125–136.
Fredriksson C, Auer RN. Kalimo H, Nordborg C, Olsson Y Johansson BB (1985) Cerebrovascular lesions in stroke-prone spontaneously hypertensive rats. Acta Neuropathol 68:284–294.
Sokrab T.E.O., Johansson B.B., Kalimi H. Olsson Y. (1998). Atransient opening of the blood-brain barrier can lead to brain damage. Extravasation of serum proteins and cellular changes in rats subjected to aortic compression. Acta Neuropathol (Berl) 75: 557–565.
Salahuddin TS, Johansson BB, Kalimo H, Olsson Y (1988) Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study. Acta Neuropathol. ( Berl ) 77: 5–13.
Johansson BB Nordborg C, Westergren I (1990) Neuronal injury after a transient operning of the blood-brain barrier: modifying factors. in Pathophysiology of the blood-brain barrier. Eds Johansson BB, Owman Ch, Widner H. Elsevier Science Publishers.
Sokrab TEO, Kalimo H, Johansson BB (1990). Parenchymal changes related to plasma protein extravasation in experimental seizures. Epilepsia 31: 1–8.
Westergren I., Nyström B., Hamberger A., Nordborg C., and Johansson B. B. (1994). Concentrations of amino acids in extracellular fluid after opening of the blood-brain barrier by intracarotid infusion of protamine sulfate. J. Neurochem. 62, 159–165.
Nordborg C, Sokrab TEO, Johansson BB (1991) The relationship between plasma protein extravasation and remote tissue changes after experimental brain infarction. Acta Neuropath 82: 118–126, 1991.
Nordborg C, Sokrab TEO, Johansson BB (1994) Oedema-related tissue damage after temporary and permanent occlusion of the middle cerebral artery. Neuropathol Appl Neurobiol 20: 56–65.
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© 1996 Springer Science+Business Media New York
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Johansson, B.B., Westergren, I., Nordborg, C. (1996). The Blood-Brain Barrier and Brain Morphology Following Insertion of a Dialysis Probe. In: Couraud, PO., Scherman, D. (eds) Biology and Physiology of the Blood-Brain Barrier. Advances in Behavioral Biology, vol 46. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9489-2_22
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DOI: https://doi.org/10.1007/978-1-4757-9489-2_22
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