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Biological Flows pp 267–286Cite as

Nonlinear Models of Coronary Flow Mechanics

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Abstract

The coronary circulation is the vascular system that supplies the heart with blood and thereby with oxygen and substrates so it can performs its task. The task of the heart is elementary to life and cessation of its performance for only a few seconds will result in unconsciousness. Cessation of blood supply to the brain exceeding 2 to 3 minutes results in irreversible brain damage. The heart itself is also vulnerable to insufficient blood supply. The body is rather inconsiderate in its demand for perfusion and the circulatory control systems drive the heart to accommodate this demand. As a result there may be circumstances that coronary blood flow is not sufficient to deliver oxygen to the heart so it can perform its task. Mostly this is the case as a result of a disease process that either reduces the upper limit of blood supply as in atheroscleroses or increases the mass of the heart to an extent that the demands for oxygen can not sufficiently be met as in hypertrophy.

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Authors and Affiliations

  1. Deparment of Medical Physics Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands

    Jos. A. E. Spaan

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  1. Jos. A. E. Spaan
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Editors and Affiliations

  1. Technological University of Compiègne, Compiègne, France

    Michel Y. Jaffrin

  2. Imperial College of Science, Technology, and Medicine, London, England

    Colin G. Caro

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Spaan, J.A.E. (1995). Nonlinear Models of Coronary Flow Mechanics. In: Jaffrin, M.Y., Caro, C.G. (eds) Biological Flows. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9471-7_14

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  • DOI: https://doi.org/10.1007/978-1-4757-9471-7_14

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