Factors Controlling the Ion Conductance of Channels

  • Marco Colombini
Part of the Ettore Majorana International Science Series book series (EMISS, volume 51)


Ion flow through membranes is not favored because it involves movement of charge through a low dielectric constant medium. The strong interaction between ions and the highly polarizable fluid, water, means that a great deal of energy is needed to remove ions from water. The low polarizability of the lipid environment in the membrane does not interact strongly with ions and therefore acts as a good barrier to ion flux. For these reasons, ion flux through membranes must be facilitated by a transport process or some polar defect in the membrane.


Bulk Phase Dextran Sulfate Alpha Helix Succinic Anhydride Access Resistance 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Marco Colombini
    • 1
  1. 1.Department of Zoology, Laboratories of Cell BiologyUniversity of MarylandCollege ParkUSA

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