Interactive Effects of Multiple Mycotoxin Contamination of Swine Diets

  • M. T. Coffey
  • W. M. HaglerJr.
  • E. E. Jones
  • J. M. Cullen
Part of the Biodeterioration Research book series (BIOR, volume 3)


Mycotoxin contamination in grains and feedstuffs is a serious agricultural and public health problem. Mycotoxins are causative agents in numerous disease syndromes in swine (Hesseltine, 1979). Over 200 mycotoxins have been identified but relatively few have been confirmed in mycotoxicoses (Tuite, 1979). Aflatoxin B1 (AFB1), which is produced by the fungal genus Aspergillus. has been studied the most extensively. Species of the genus Fusarium that produce zearalenone (ZE) and trichothecene toxins (T-2 toxin and deoxynivalenol) are common in many plant materials. At the present time, even a cursory examination of the scientific literature leads to the conclusion that mycotoxins from these two genera are responsible for most of the adverse effects on swine production. Subacute exposure of swine to these toxins adversely affects health, growth, and reproduction (Hintz et al., 1967; Christensen et al., 1972; Chang et al., 1979), all of which are important determinants of profitability.


Average Daily Gain Growth Depression Mycotoxin Contamination Swine Production Trichothecene Toxin 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • M. T. Coffey
    • 1
  • W. M. HaglerJr.
    • 2
  • E. E. Jones
    • 3
  • J. M. Cullen
    • 4
  1. 1.Department of Animal ScienceNorth Carolina State UniversityRaleighUSA
  2. 2.Mycotoxin Laboratory, Department of Poultry ScienceNorth Carolina State UniversityRaleighUSA
  3. 3.Departments of Animal Science and BiochemistryNorth Carolina State UniversityRaleighUSA
  4. 4.College of Veterinary MedicineNorth Carolina State UniversityRaleighUSA

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