Quantifying Naturally-Occurrrng Macrocyclic Trichothecene Toxins

  • A. Bata
  • W. V. Dashek
  • G. C. Llewellyn
  • T. F. Cheatle
  • C. E. O’Rear
  • B. Harrach
Part of the Biodeterioration Research book series (BIOR, volume 3)


Macrocyclic trichothecene mycotoxins (Figure 1) are toxic metabolites produced by the fungi, Stachybotrys and Myrothecium (Bambarg and Strong, 1972; Jarvis et al., 1980). These fungi are considered both causative agents of stachybotryotoxicosis and plant pathogens. Various reports have appeared concerning macrocyclic trichothecene-induced mycotoxicosis and stachybotryotoxicosis (Adnrassy et al., 1980; Danko, 1976; Harrach et al., 1983; Schneider et al., 1979). These diseases have occurred in various regions of the world, e.g., South Africa (Schneider et al., 1979), Finnland (Hintikka, 1977), the Soviet Union (Yuskiv, 1968), and Hungary (Danko, 1976; Harrach et al., 1983). In addition, fungal strains which produce macrocyclic trichothecenes have been detected in Poland, East Germany, Hungary, Czechoslovakia, India, and Egypt. Therefore, the macrocyclic trichothecenes appear to be widely distributed.


High Performance Liquid Chromatography High Performance Liquid Chromatography Brine Shrimp High Performance Liquid Chromatography Separation Straw Sample 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • A. Bata
    • 1
  • W. V. Dashek
    • 2
  • G. C. Llewellyn
    • 3
  • T. F. Cheatle
    • 4
  • C. E. O’Rear
    • 5
  • B. Harrach
    • 6
  1. 1.Department of Biochemistry and Food TechnologyTechnical University BudapestBudapestHungary
  2. 2.Department of BiologyClark Atlanta UniversityAtlantaUSA
  3. 3.Virginia Department of HealthBureau of Toxic SubstancesRichmondUSA
  4. 4.Department of BiologyVirginia Commonwealth UniversityRichmondUSA
  5. 5.Department of Forensic SciencesThe George Washington UniversityUSA
  6. 6.Department of Biochemistry and Food TechnologyTechnical University BudapestBudapestHungary

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