Studies on Fusarium Moniliforme: Causal Agent of Equine Leucoencephalomalacia

  • Cecile E. F. Le Grenade
  • George A. Bean
Part of the Biodeterioration Research book series (BIOR, volume 4)


For almost a hundred years, a fatal neurological disease affecting horses, donkeys and mules has been occurring (Butler, 1902). The disease, called equine leucoencephalomalacia (ELEM), is characterized by the presence of liquefactive necrotic lesions primarily in the white matter of the cerebral hemispheres of the brain of affected horses (Haliburton et al., 1979). Feeding studies have shown that mold-infected corn or corn fodder is a constant factor associated with ELEM outbreaks.


Fusarium Species Feed Sample Fusaric Acid Baby Hamster Kidney Fusarium Moniliforme 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Cecile E. F. Le Grenade
    • 1
  • George A. Bean
    • 2
  1. 1.Division of MicrobiologyFood and Drug AdministrationUSA
  2. 2.Department of BotanyUniversity of MarylandCollege ParkUSA

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