Biochemistry pp 453-475 | Cite as

Transcription—The Synthesis of RNA

  • J. Stenesh


Synthesis of messenger RNA by transcription of the genetic information contained in DNA constitutes the first stage of protein biosynthesis. In the second stage (translation), mRNA serves as the template that directs amino acid polymerization. The term transcription is well chosen: a sequence of deoxyribonucleotides in DNA becomes transcribed into a sequence of ribonucleotides in RNA. Transcription retains the genetic information in the form of nucleotide sequences but alters the type of nucleotide. In addition to generating mRNAs, transcription produces ribosomal, transfer, and small RNAs. The basic mechanism of transcription is similar in all cells and requires catalysis by RNA polymerase (DNA-dependent RNA polymerase).


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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • J. Stenesh
    • 1
  1. 1.Western Michigan UniversityKalamazooUSA

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