Free energy changes of chemical reactions are related to a number of parameters: entropy and enthalpy changes (Eq. 9.1), equilibrium constants (Eq. 9.2), and oxidation-reduction potentials. Of these, equilibrium constants and oxidation-reduction potentials are of primary importance for computing free energy changes of metabolic reactions. Relationships between free energy changes and equilibrium constants were explored in Chapter 9. Now we will focus on the relationships between free energy changes and oxidation-reduction potentials.
KeywordsOxidative Phosphorylation Cytochrome Oxidase Free Energy Change Electron Carrier Citric Acid Cycle
Unable to display preview. Download preview PDF.
- Bensasson, R. V., Land, E. J., and Truscott, T. G., Excited States and Free Radicals in Biology and Medicine, Oxford University Press, Oxford (1993).Google Scholar
- Fetter, J. R., et al.,Possible proton relay pathways in cytochrome c oxidase, Proc. Natl. Acad Sci. USA 92:1604–1608 (1995).Google Scholar
- Rees, D. C., and Farrelly, D., Biological electron transfer, in The Enzymes, 3rd ed. (D. S. Sigman and P. D. Boyer, eds.), Vol. 19, pp. 38–97, Academic Press, New York (1990).Google Scholar
- Stenesh, J., Core Topics in Biochemistry, Cogno Press, Kalamazoo, MI (1993).Google Scholar