Non-Peroxide Antibacterial Activity of Honey

  • Stefan Bogdanov


Honey acts as an antibacterial agent against many bacteria (1). There are two sorts of antibacterial agents or so called “inhibines.” One of them is heat- and light-sensitive and has its origin in the H2O2, produced by honey glucose oxidase (2,3,4). Some workers believe that hydrogen peroxide is the main antibacterial agent (2,5,6). Other authors find that the non-peroxide activity is the more important one (7,8,9). The H2O2 amount in honey is very small and it can be produced only after aerobic incubation of diluted honey solutions, which might mean that it is not very important for the antibacterial action of honey (10). The argumentations of the pro and contra peroxide side are based on the results with the specific antibacterial test used. However, a certain antibacterial test might be sensitive only to certain types of antibacterian substances. In a previous study from our laboratory it was found that while in an agar disc diffusion test only the peroxide activity was measured, in a liquid medium test only the non-peroxide substances were active(10).


Antibacterial Activity Honey Sample Royal Jelly Antibacterial Substance Honey Solution 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Stefan Bogdanov
    • 1
  1. 1.Bee DepartmentFederal Dairy Research InstituteLiebefeldSwitzerland

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