“Three for one” — a Simple Growth Mechanism that Guarantees a Precise Copy of the Thin, Rod-Shaped Murein Sacculus of Escherichia coli
During growth and division of Escherichia coli the stress-bearing rod-shaped murein sacculus necessarily has to be elongated and divided into two intact daughter sacculi. For Gram-positive rods such as Bacillus subtilis it has been shown that this is accomplished by an inside-to-outside growth mechanism (Koch and Doyle, 1985). It is based on the presence of a thick multi-layered murein shell which is characteristic for this group of bacteria. The thin murein layer of Gram-negative bacteria demands for a different, more sophisticated mechanism.
KeywordsTemplate Strand Glycan Chain Patching Model FtsZ Ring Murein Hydrolase
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