Regulation of the Morphogenetic Cycle of Escherichia coli: 1992

  • William D. Donachie
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 65)


In exponentially increasing populations, the individual rod-shaped cells of E. coli grow by continuous elongation (without significant change in diameter) and divide by the formation of a centrally placed septum after each successive doubling in length and volume. Many of the genes and proteins which are specifically required for this morphogenetic cycle are now known (see Table) but the way in which their activities are regulated remains largely unknown. What follows is a brief synopsis of the present picture. (Only a few more recent and key references are given; earlier references can be obtained from recent reviews, e.g. Matsuhashi et al. 1990, Donachie & Begg 1990.)


EnvA Protein Chromosome Replication Septum Formation Alanine Racemase FtsZ Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • William D. Donachie
    • 1
  1. 1.Institute of Cell and Molecular BiologyUniversity of EdinburghEdinburghScotland

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