In Enterobacter Cloacae Alterations Induced by Glycine and d-Amino Acids in the Composition and Structure of Peptidoglycan Are Accompanied by Induction of Chromosomal β-Lactamase: A Model Involving ftsZ and Septation

  • Abramo C. Ottolenghi
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 65)


The induction of Class I β-lactamase (Bla) in the Enterobacteriaceae and other Gram negative organisms has been studied extensively but as yet no information is available as to the nature of the event(s) which triggers it nor of the specific molecule that might act as the inducer. It is the purpose of this paper to present evidence and to suggest a model which makes septation/division the controlling factor for the induction of Bla.


Nalidixic Acid Enterobacter Cloaca Penicillin Binding Protein Division Gene Peptidoglycan Synthesis 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Abramo C. Ottolenghi
    • 1
  1. 1.Department of Medical Microbiology and ImmunologyThe Ohio State UniversityColumbusUSA

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