Observing Reactions via Flow Injection Scanning Tunneling Microscopy

  • James D. Noll
  • Paul G. Van Patten
  • M. L. Myrick


The scanning tunneling microscope (STM) is used to view conductive and semiconductive surfaces to obtain topographic and structural information. A number of literature reports describe molecules absorbed on surfaces. We describe a flow injection system which allows imaging before, during, and after a surface reaction. The flow injection system consists of a flow cell in which a solution is pumped over a sample via a flow injector and a peristaltic pump during STM imaging. Results indicate that atomic imaging can be maintained under a rapidly-flowing solution stream. This system can provide a way to observe reactions occurring on surfaces. Preliminary applications of the system that include the etching of a metal surface, attachment of thiols on a gold surface, and attachment of polymers onto highly ordered pyrolytic graphite (HOPG) step defects are described.


Scanning Tunneling Microscope Peristaltic Pump Flow Cell Gold Surface Tunneling Microscopy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    J.S. Foster, J.E. Frommer, and P.C. Arnett, Monecular manipulation using a tunnelling microscope, Nature, 331: 324–326 (1988).CrossRefGoogle Scholar
  2. 2.
    Y.L. Lyubchenko, S.M. Lindsay, J.A. DeRose, and T. Thundat, A technique for stable adhesion of DNA to a modified graphite surface for imaging by scanning tunneling microscopy“ J. Vac. Sci. Technol. A9: 1288–1290 (1991).CrossRefGoogle Scholar
  3. 3.
    M. G. Youngquist, R. J. Driscoll, T.R. Coley, W.A. Goddard, and.1.D. Baldeschwieler, Scanning tunneling microscopy of DNA atom-resolved imaging general observation and possible contrast mechanism, J. Yac. Sci. Technol., A9: 1304–1308 (1991).Google Scholar
  4. 4.
    W. Li, J.A. Virtanen, and R.M. Penner, A nanometer-scale galvanic cell, J. Phys. Chem., 96: 6529–6532 (1992).CrossRefGoogle Scholar
  5. 5.
    J. F. Womelsdorf, W. C. Ermler, and C. J. Sandroff, Imaging of colloidal gold on graphite by scanning tunneling microscopy: isolated particles, aggregates, and ordered arrays, J. Phys. Chem., 95: 503–505 (1991).CrossRefGoogle Scholar
  6. 6.
    T. J. McMaster, H. Carr, M. J. Miles, P. Cairns, and V. J. Morris, Polypeptide structures imaged by the scanning tunneling microscope, J. Vac. Sci. Technol., A8: 648–651 ( 1990.Google Scholar
  7. 7.
    C. R. Clemmer and T. P. Beebe, Graphite: A mimic for DNA and other biomolecules in scanning tunneling microscope studies, Science, 251: 640–642 (1991).CrossRefGoogle Scholar
  8. 8.
    M. L. Myrick, N.V. Hud, S. M. Angel, and D.G. Garvis, Chemical Physics Letters, 180: 156–160 (1991).CrossRefGoogle Scholar
  9. 9.
    T. Yoshimura, S. Tatsuura, and W. Sotoyama, Polymer films formed with monolayers growth steps by molecular layer deposition, Appl. Phys. Leu., 59: 482–484 (1991).CrossRefGoogle Scholar
  10. 10.
    Y.T. Kim and A. J. Bard, Imaging and etching of se110-assembled n-Octadecanethiol layers on gold with the scanning tunneling microscope,“ Langmuir, 8: 1096–1102 (1992).CrossRefGoogle Scholar
  11. 11.
    C.A. Widrig, C.A. Alves, M.D. Porter, Scanning tunneling microscopy of ethanethiolate and nOctadecanethiolate Monolayers spontaneously abserbed at gold surfaces, J. Anl. Chem. Soc. 113: 2805–2810 (1991).CrossRefGoogle Scholar
  12. 12.
    N. J. Tao and S.M. Linsay, Observations of the 22x30.5 reconstruction of Au(111) under aqueous solutions using scanning tunnelling microscope,“ J. Appl. Phys. 70: 5141–5143 (1991).CrossRefGoogle Scholar
  13. 13.
    J.D. Noll. J.B. Cooper, and M.L. Myrick, Analysis of highly ordered pyrolytic graphite step defects via scanning tunneling microscopy, J. Vac. Sci. Tech. B, B11: 2006–2011 (1993).CrossRefGoogle Scholar
  14. 14.
    T. Yoshimura, S. Tatsuura, and W. Sotoyama, Polymer films formed with monolayers gorwth steps by molecular layer deposition, Appl. Phys. Len., 59: 482–484 (1991).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • James D. Noll
    • 1
  • Paul G. Van Patten
    • 1
  • M. L. Myrick
    • 1
  1. 1.Department of Chemistry and BiochemistryUniversity of South CarolinaColumbiaUSA

Personalised recommendations