Scanning Force Microscopy on Living Virus-Infected Cells

  • W. Häberle
  • D. P. E. Smith
  • J. K. H. Hörber
  • C. P. Czerny


Using scanning force microscopy (SFM), it is possible to follow processes on the membrane of single living cells. Monkey kidney cells were imaged under normal growth conditions with a resolution of approximately 10 nm. Upon adding a suspension of pox virus, pronounced changes in the cell membrane were observed. Image sequences of these processes on the cell surface can be monitored over time. The cell membrane was studied to determine how it is affected by changes in temperature. The end of the micropipette holding the cell was also examined by SFM.


Vaccinia Virus Monkey Kidney Cell Single Living Cell Patch Clamp Pipette Scanning Force Microscopy Image 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • W. Häberle
    • 1
  • D. P. E. Smith
    • 1
  • J. K. H. Hörber
    • 2
  • C. P. Czerny
    • 3
  1. 1.IBM Research DivisionMunich Physics GroupMunich 40Germany
  2. 2.EMBLHeidelbergGermany
  3. 3.Tierärztliche FakultätLudwig-Maximillians-UniversitätMunich 22Germany

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