Abstract
Lentiviruses arc nononcogenic retroviruses that cause chronic disease in persistently infected individuals. The viruses are transmitted exogenously and replicate productively in terminally differentiated cells of the immune system. Lentiviruses are transmitted in body fluids and infection often remains inapparent for months or years. Disease begins insidiously and infected individuals eventually develop a chronic multisystemic disease manifest as wasting, immune dysfunction, dyspnea, or neurologic impairment. The viruses are species-specific and members of this group infect a variety of hosts causing unique disease syndromes in each host species. However, the members of the lentivirus group share a remarkable number of biologic, morphologic, and structural features which define this subfamily of viruses (Narayan and Clements, 1987; Haase, 1986).
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Huso, D.L., Narayan, O. (1990). Escape of Lentiviruses from Immune Surveillance. In: Kurstak, E., Marusyk, R.G., Murphy, F.A., Van Regenmortel, M.H.V. (eds) Virus Variability, Epidemiology and Control. Applied Virology Research, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9271-3_5
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