Immune Responses to Synthetic Peptide Vaccines of Veterinary Importance
Vaccination against virus diseases has been one of the major triumphs of modern medicine. However, even with great success in some areas, many viral diseases continue to plague human and animal populations. Some of the reasons for the inability to control viral infections are related to the epidemiology of the infection and the pathogenesis of the specific disease in question. Other impediments to producing effective vaccines are (1) it is difficult to grow sufficient quantities of virus in vitro; and (2) if they do grow, some viruses are extremely labile and may be inactivated prior to administration. A final problem with production of conventional vaccines is that the causitive agent may be dangerous to manipulate in the laboratory. The use of synthetic peptides as vaccines has been suggested as an alternate approach to induce immunity to a wide variety of different virus diseases while avoiding many of the problems mentioned above (Brown, 1984).
KeywordsSynthetic Peptide Approximate Molecular Weight Free Peptide Peptide Gp41 Induce Neutralize Antibody
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