Digoxigenin Labeled Probes and their Use in the Laboratory Diagnosis of Virus Infections

  • Pirkko Heino
  • Veijo Hukkanen
  • Pertti P. Arstila
Part of the Applied Virology Research book series (AVIR, volume 3)


The last few years have seen a rapid spread of a novel nonisotopic label, digoxigenin (DIG), in use for nucleic acid hybridizations. Nucleic acid hybridization has been, and still is, the basic method in modern molecular biology. Most applications involve the use of radiolabeled-probes. Radioisotope labels are sensitive and well established for laboratory use, but on the other hand the labels are short-lived and special facilities and equipment are required for handling of isotopes. In most countries there are strict regulations for the use of radioactive materials.


Human Immunodeficiency Virus Polymerase Chain Reaction Product Human Papilloma Virus Human Papilloma Virus Infection Nucleic Acid Hybridization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Pirkko Heino
    • 1
  • Veijo Hukkanen
    • 2
  • Pertti P. Arstila
    • 2
  1. 1.Department of VirologyKarolinska InstituteStockholmSweden
  2. 2.Department of VirologyUniversity of TurkuTurkuFinland

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