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Oxygenation by Methane Monooxygenase: Oxygen Activation and Component Interactions

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Applications of Enzyme Biotechnology

Abstract

Methanotrophic bacteria possess the unique ability to utilize methane as the sole source of carbon and energy. Indeed, methane is the only carbon source capable of sustaining vigorous and long term growth of these organisms1. The methanolytic activity of methanotrophs can be ascribed to the elaboration of a unique enzyme, methane monooxygenase2 (MMO), which catalyzes the following reaction:

$$ Methane + {O_2} + NADH + {H^ + } \to NA{D^ + } + {H_2}O + Methanol $$

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Authors and Affiliations

  1. Department of Biochemistry, Medical School, University of Minnesota, Minneapolis, MN, 55455, USA

    Wayne A. Froland, Kristoffer K. Andersson, Sang-Kyu Lee, Yi Liu & John D. Lipscomb

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  1. Wayne A. Froland
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  3. Sang-Kyu Lee
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  1. Texas A&M University, College Station, Texas, USA

    Jeffery W. Kelly  & Thomas O. Baldwin  & 

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© 1991 Springer Science+Business Media New York

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Froland, W.A., Andersson, K.K., Lee, SK., Liu, Y., Lipscomb, J.D. (1991). Oxygenation by Methane Monooxygenase: Oxygen Activation and Component Interactions. In: Kelly, J.W., Baldwin, T.O. (eds) Applications of Enzyme Biotechnology. Industry-University Cooperative Chemistry Program Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9235-5_4

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  • DOI: https://doi.org/10.1007/978-1-4757-9235-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9237-9

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