Oxygenation by Methane Monooxygenase: Oxygen Activation and Component Interactions

  • Wayne A. Froland
  • Kristoffer K. Andersson
  • Sang-Kyu Lee
  • Yi Liu
  • John D. Lipscomb
Part of the Industry-University Cooperative Chemistry Program Symposia book series (IUCC)


Methanotrophic bacteria possess the unique ability to utilize methane as the sole source of carbon and energy. Indeed, methane is the only carbon source capable of sustaining vigorous and long term growth of these organisms1. The methanolytic activity of methanotrophs can be ascribed to the elaboration of a unique enzyme, methane monooxygenase2 (MMO), which catalyzes the following reaction:
$$ Methane + {O_2} + NADH + {H^ + } \to NA{D^ + } + {H_2}O + Methanol $$


Product Distribution Mossbauer Spectrum Methane MONOOXYGENASE Hydrogen Atom Abstraction Mixed Valent State 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Wayne A. Froland
    • 1
  • Kristoffer K. Andersson
    • 1
  • Sang-Kyu Lee
    • 1
  • Yi Liu
    • 1
  • John D. Lipscomb
    • 1
  1. 1.Department of Biochemistry, Medical SchoolUniversity of MinnesotaMinneapolisUSA

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