Subclinical Shedding of HSV: Its Potential for Reduction by Antiviral Therapy

  • Lawrence Corey
  • Anna Wald
  • L. Gray Davis
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 394)


Several recent serosurveys have indicated that the prevalence of HSV-2 infection is continuing to increase (Table 1)1–5. The prevalence of HSV-2 is high in many populations. In Seattle, 43% of women and 35% of men attending STD clinics have already acquired HSV-2 infection, while in British STD clinic attendees, the figures are 37% and 27%. Breinig et al reported that 21% of women attending family planning clinics were HSV-2 seropositive3. Perhaps the most definitive work in this area is a recent population based serosurvey of the US adults which has shown that the overall seroprevalence of HSV-2 has risen from 16.4% in 1978 to 21.7% in 1990; a 32% increase in HSV-2 seropositivity in the last decade6.


Genital Herpes South CarolIna Genital Lesion Penile Skin Recurrent Genital Herpes 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Lawrence Corey
  • Anna Wald
  • L. Gray Davis

There are no affiliations available

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