Therapy for Chronic Hepatitis B Infection

  • Norah A. Terrault
  • Teresa L. Wright
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 394)


There are many parallels between hepatitis B virus (HBV) infection and that of human immunodeficiency virus (HIV). HBV is a partially double-stranded DNA virus which replicates through an RNA intermediate to produce viral DNA, a process which requires a viral reverse transcriptase. Hence reverse transcriptase inhibitors which are effective for HIV infection may also be active toward HBV. HBV is transmitted by the same mechanisms as is HIV (sexual, parenteral and perinatal exposure) and hence there are many similarities in the epidemiology of these two viruses. Like patients with HIV infection, patients with chronic HBV infection are at risk of developing complications after years or even decades of infection.


Chronic Hepatitis Chronic Active Hepatitis Million Unit Active Viral Replication Duck Hepatitis 
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© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Norah A. Terrault
  • Teresa L. Wright

There are no affiliations available

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