Prophylaxis and Treatment of CMV Infections in Transplantation

  • John A. Zaia
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 394)


Human cytomegalovirus [CMV] infection is a common occurrence in persons with or without immunocompromising diseases or treatments, but CMV rarely produces disease in the immunocompetent individual1 When disease does occur it is usually associated with unusual situations such as fetal life, post-trauma or post-surgical exposure to primary CMV infection, or in the young adult with children in day-care.2 Thus, in normal persons, symptomatic disease occurs only following primary infection, and the most severe diseases are only seen in association with other compromising medical conditions. This is true also in recipients of marrow or solid organ transplants in which primary infection and degree of immunocompetence are the most important factors for determining outcome


Transplant Recipient Liver Transplant Recipient Cytomegalovirus Infection Oral Acyclovir Cytomegalovirus Disease 
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© Springer Science+Business Media New York 1996

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  • John A. Zaia

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