Antimicrobial Susceptibility Tests: Testing Methods and Interpretive Problems

  • Patrick R. Murray
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 349)


Infectious diseases are a leading cause of morbidity and mortality in hospitalized patients. This fact places a tremendous burden on the clinical microbiology laboratory to diagnose rapidly the etiologic agent(s) responsible for a patient’s infection and provide therapeutic guidance for eradication of the organism(s). Laboratories are asked not only to perform these tasks with precision and rapidity, but also in a cost-effective manner in an era of increasing emphasis on reduction of laboratory expenses. Physicians will pose the question — How accurately can antimicrobial susceptibility tests predict clinical outcome? At the same time, the microbiologists ask — What method should we use for performing susceptibility tests? What is the most accurate method? What is the most cost — effective method? What are the limitations of the in vitro tests? I will try to address these questions in the following discussion.


Susceptibility Test Disk Diffusion Antimicrobial Susceptibility Test Disk Diffusion Test Diagn Microbiol Infect 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Patrick R. Murray
    • 1
  1. 1.Washington University School of MedicineSaint LouisUSA

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