The Evolution of Antimicrobial Susceptibility Testing Methods

  • James A. Poupard
  • Stephen F. Rittenhouse
  • Lori R. Walsh
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 349)


It is reasonable to conclude that antibiotic testing did not precede the concept of antibiotics, therefore, it is logical to start the review with penicillin and the work of Alexander Fleming. It should be noted that the history of antibiotic testing is no different than other topics in the history of science, there are always relevant predecessors to whatever event is chosen as the starting point for the subject. It would be negligent to fail to mention the work of Paul Ehrlich as well as several early observations that seem worthy of note before focusing on the evolution of the events leading to the contemporary field of antimicrobial susceptibility testing.


Susceptibility Testing Disk Diffusion Clinical Microbiology Antimicrobial Susceptibility Testing Broth Dilution 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • James A. Poupard
    • 1
  • Stephen F. Rittenhouse
    • 1
  • Lori R. Walsh
    • 2
  1. 1.SmithKline BeechamKing of PrussiaUSA
  2. 2.Abington Memorial HospitalAbingtonUSA

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