Abstract
Infections in the female genital tract arise from a variety of sources. In pregnant women, infections tend to occur at parturition—especially after cesarean section. In the non-pregnant adult, some of these infections are spontaneous or the sequela of sexually transmitted disease. Others are related to anatomical problems with the genitals or to surgical processes. Variations in the distribution and susceptibility patterns of community or hospital acquired infections have led to changes in the use of antimicrobials for ambulatory and hospitalized patients. We report on the susceptibility to a number of antibiotics of a variety of organisms isolated from endocervical or deeper cultures of women with acute pelvic inflammatory disease (PID) or endomyometritis. We also review the information regarding trends in antimicrobial susceptibility for bacteria involved with female genital infections.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
R.L. Sweet and R.S. Gibbs. 1985. pp. 127–141. Infectious diseases of the female genital tract. Williams and Wilkins, Baltimore, Md.
Centers for Disease Control and Prevention. 1993. 1993 Sexually transmitted diseases treatment guidelines. Morbid. Mortal. Weekly Rep. 42 RR-14: 50–66.
G.W. Counts. 1988. Cefoxitin: its role in treatment and prophylaxis of obstetric and gynecologic infections. Rev. Infect. Dis. 10: 76–91.
R.L. Sweet and W.J. Ledger. 1979. Cefoxitin: Single-agent treatment of mixed aerobic-anaerobic pelvic infections. Obstet. and Gynec. 54: 193–198.
M.B. Hasselquist and S. Hillier. 1991. Susceptibility of upper-genital tract isolates from women with pelvic inflammatory disease to ampicillin, cefpodoxime, metronidazole, and doxycycline. Sex. Trans. Dis. 18: 146–149.
M.L. Maccato, S. Faro, M.G. Martens, and H.A. Hammill. 1991. Ciprofloxacin versus gentamicin/clindamycin for postpartum endometritis. J. Reprod. Med. 36: 857–861.
K. Rosene, D.A. Eschenbach, L.S.. Tompkins, G.E. Kenny, and H. Watkins. 1986. Polymicrobial early postpartum endometritis with facultative and anaerobic bacteria, genital mycoplasmas, and Chlamydia trachomatis: treatment with piperacillin or cefoxitin. J. Infect. Dis. 153: 1028–1045.
R.L. Sweet, M.O. Robbie, M. Ohm-Smith, and W.K. Hadley. 1983. Comparative study of piperacillin versus cefoxitin in the treatment of obstetric and gynecologic infections. Am. J. Obstet. Gynecol. 145: 342–349.
J.G. Pastorek and C.V. Sanders, Jr. 1991. Antibiotic therapy for postcesarean endomyometritis. Rev. Infect. Dis. 13 (Suppl 9): S752–757.
P. Summanen. 1993. Recent taxonomic changes for anaerobic gram-positive and selected gram-negative organisms. Rev. Infect. Dis. 1993 (Suppl 4): S168–174.
W.R. Crombleholme, J. Schachter, M. Ohm-Smith, J. Luft, R. Whidden, and R.L. Sweet. 1989. Efficacy of single-agent therapy for the treatment of acute pelvic infalmmatory disease with ciprofloxacin. Am J. Med. 87 (Suppl 5A): 142S - 147S.
T. Fekete. 1993. Antimicrobial susceptibility testing of Neisseria gonorrhoeae and implications for epidemiology and treatment. Clin. Microbiol. Rev. 6: 22–33.
J.H. Tiedemann, J.F. Hackney, and E.V. Price. 1965. Acute gonorrheal urethritis in men: treatment with spectinomycin sulfate. JAMA 191: 101–103.
J.M. Ehret and F.N. Judson. 1988. Susceptibility testing of Chlamydia trachomatis: from eggs to monoclonal antibodies. Antimicrob. Agents Chemother. 32: 129–599.
L. Slaney, H. Chubb, A. Ronald, and R. Brunham. 1990. In-vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and Chlamydia trachomatis. J. Antimicro. Chemother. 25 (Suppl A): 1–5.
R.B. Jones, B. Van der Pol, D.H. Martin, and M.K. Shepard. 1990. Partial characterization of Chlamydia trachomatis isolates resistant to multiple antibiotics. J. Infect. Dis. 162: 1309–1315.
R.N. Jones. 1989. Cefmetazole (CS-1170), a “new” cephamycin with a decade of clinical experience. Diagn. Microbiol. Infect. Dis. 12: 367–379.
R.C. Brunham, B. Binns, F. Guijon, D. Danforth, M.L. Kosseim, R. Rand, J. McDowell, and E. Rayner. 1988. Etiology and outcome of pelvic inflammatory disease. J. Infect. Dis. 158: 510–517.
C.K. Walker, J.G. Kahn, A.E. Washington, H.B. Peterson, and R.L. Sweet. 1993. Pelvic inflammatory disease: metaanalysis of antimicrobial regimen efficacy. J. Infect. Dis. 168: 969–78.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer Science+Business Media New York
About this chapter
Cite this chapter
Tumah, H., Woodwell, J., Chatwani, A., Truant, A., Fekete, T. (1995). Patterns of Resistance in Organisms Causing Gynecologic Infections. In: Jungkind, D.L., Mortensen, J.E., Fraimow, H.S., Calandra, G.B. (eds) Antimicrobial Resistance. Advances in Experimental Medicine and Biology, vol 390. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9203-4_14
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9203-4_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9205-8
Online ISBN: 978-1-4757-9203-4
eBook Packages: Springer Book Archive