Molecular Epidemiologic Analysis of Antibiotic Resistant Microorganisms

  • Joseph F. JohnJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 390)


Antibiotic resistance presents a specific, readily available marker to use in the epidemiologic analysis of microorganisms. Historically, most epidemics like bubonic plague, cholera, influenza, and meningococcal infection involved microorganisms not subjected to the selective pressures of therapeutic antimicrobials. For such outbreaks, there were no antimicrobial resistance markers typifying the outbreak strains. Modern antimicrobial chemotherapy has brought with it selective pressures that favor emergence of resistant clones, whose phenotypic traits thereby provide the epidemiologist and clinical microbiologist with distinctive phenotypic and genotypic traits in these microorganisms.


Molecular Epidemiology Acinetobacter Baumannii Outbreak Strain Infect Control Hosp Hosp Infect 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Joseph F. JohnJr.
    • 1
  1. 1.Molecular Genetics and MicrobiologyRobert Wood Johnson Medical SchoolNew BrunswickUSA

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