Angiogenesis pp 125-134 | Cite as

Regulation of Angiogenesis: The Role of Protein Kinase, Nitric Oxide, Thrombin and Basement Membrane Synthesis

  • M. E. Maragoudakis
  • N. E. Tsopanoglou
  • G. C. Haralabopoulos
  • E. Sakkoula
  • E. Pipili-Synetos
  • E. Missirlis
Part of the NATO ASI Series book series (NSSA, volume 263)


Angiogenesis plays a key role in the pathology of many disease states (Folkman and Shing, 1992). Practically every medical specialty deals with disease states where a derangement of angiogenesis is evident. In addition, angiogenesis is a prominent event in many physiological processes such as the establishment of placenta, the changes in the mammary gland during lactation and in the endometrium during ovulation (Auerbach et al., 1991). Angiogenesis is also important in wound healing and repair processes (Knighton et al., 1990).


Nitric Oxide Titanocene Dichloride Blood Clotting Cascade Physiological Angiogenesis Angiogenic Cascade 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • M. E. Maragoudakis
    • 1
  • N. E. Tsopanoglou
    • 1
  • G. C. Haralabopoulos
    • 1
  • E. Sakkoula
    • 1
  • E. Pipili-Synetos
    • 1
  • E. Missirlis
    • 1
  1. 1.Department of PharmacologyUniversity of Patras Medical SchoolRio PatrasGreece

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