Abstract
Endothelial cells interact with various cell types and with extracellular matrices; both types of interactions are important for their functional integrity. Most endothelial cells are underlined by a basement membrane, which is a very specialized form of extracellular matrix. It contains several macromolecules present exclusively in it and absent from any other extracellular matrix compartment. These macromolecules are: type IV collagen, laminin, entactin/nidogen, perlekan(a form of heparan sulfate proteoglycan), chondroitin sulfate proteoglycan. Most of them exist in various isoforms which interact in complicated ways to form the heteropolymeric and heterogeneous structure which is defined as basement membranel.
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References
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© 1994 Springer Science+Business Media New York
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Charonis, A. et al. (1994). A Novel Laminin Domain Involved in Adhesion of Endothelial Cells. In: Maragoudakis, M.E., Gullino, P.M., Lelkes, P.I. (eds) Angiogenesis. NATO ASI Series, vol 263. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9188-4_15
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DOI: https://doi.org/10.1007/978-1-4757-9188-4_15
Publisher Name: Springer, Boston, MA
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