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Altered Proliferation of Retinal Microvascular Cells in Response to Non-Enzymatic Glycosylated Matrix Proteins

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Angiogenesis

Part of the book series: NATO ASI Series ((NSSA,volume 263))

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Abstract

Diabetic retinopathy is characterized by microaneyrisms derived from vessels which have selectively lost their pericytes and demonstrate focal proliferation of endothelial cells. The proliferation of retinal endothelial cells and the pericytic degeneration followed by replacement with pericytic “ghosts” is an almost invariable and early feature of diabetic retinopathy 1.

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© 1994 Springer Science+Business Media New York

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Kalfa, T.A., Gerritsen, M.E., Tsilibary, E.C. (1994). Altered Proliferation of Retinal Microvascular Cells in Response to Non-Enzymatic Glycosylated Matrix Proteins. In: Maragoudakis, M.E., Gullino, P.M., Lelkes, P.I. (eds) Angiogenesis. NATO ASI Series, vol 263. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9188-4_14

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  • DOI: https://doi.org/10.1007/978-1-4757-9188-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9190-7

  • Online ISBN: 978-1-4757-9188-4

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