Abstract
Under physiological circumstances the ability of a given tissue to produce a neovascular response is under strict control, i.e. the balance between factors and events favoring or interfering with neovascular growth is in equilibrium. Modification of the normal cell/cell and cell/matrix boundaries, which maintain tubular morphology of the endothelium at the postcapillary level, is a prerequisite for capillary endothelial cell mobilization and proliferation to constitute a neovascular response.
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Ziche, M. et al. (1994). The Proliferative Effect of Substance P on Capillary Endothelial Cells is Mediated by Nitric Oxide. In: Maragoudakis, M.E., Gullino, P.M., Lelkes, P.I. (eds) Angiogenesis. NATO ASI Series, vol 263. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9188-4_11
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DOI: https://doi.org/10.1007/978-1-4757-9188-4_11
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