Expression of the M-Subunit of Laminin Correlates with Increased Cell Adhesion and Metastatic Propensity

  • Wheamei Jenq
  • Shi-Jun Wu
  • Nicholas A. Kefalides
Part of the NATO ASI Series book series (NSSA, volume 263)


The presence of several isoforms of laminin in a variety of tissues and species has been reported. S-laminin, a B1 chain homologue of 190 kDa, has been identified in association with the synaptic cleft of the neuromuscular junction (Hunter, et al., 1989), while O’Rear (1992) has reported a novel laminin B1 chain variant (B1-2) in the avian eye, and Marinkovich et al. (1992) reported another variant, K-laminin in human amniotic fluid.


Human Placenta Human Amniotic Fluid Slot Blot Hybridization Metastatic Propensity Placental Basement Membrane 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Wheamei Jenq
    • 1
  • Shi-Jun Wu
    • 1
  • Nicholas A. Kefalides
    • 1
  1. 1.Connective Tissue Research Institute and Department of MedicineUniversity of Pennsylvania, and University City Science CenterPhiladelphiaUSA

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