Summary
In ours series 1) no relationship between ulcerative colitis (UC) activity and antineutrophil cytoplasmic auto-antibodies (ANCA) monitored by indirect immunofluorescence was observed in sera from 25 repeatedly tested patients with UC 2) ANCA did not appear as being potentially a genetic marker of susceptibility to UC as previously reported.
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References
Saxon, A., Shanahan, F., Landers, C., Ganz, T., Targan, S., 1990, A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease, J Allergy Clin Immunol. 86: 202–10
Duerr, R.H., Targan, S., Landers, C.J., Sutherland, R., Shanahan, F., 1991, Neutrophil autoantibodies in ulcerative colitis: comparison with other colitides/diarrheal diseases, Gastroenterology 100: 1590–6
Colombel, J.F., Reumaux, D., Duthilleul, P., Noel, L.H., Gower-Rousseau, C., Paris, J.C., Cortot, A., 1992, Antineutrophil cytoplasmic auto-antibodies in inflammatory bowel disease, Gastroenterol Clin Biol. 16: 656–660
Rump, J.A., Schölmerich, J., Gross, V., Roth, M., Helfesrieder, R., Rautmann, A., Lüdemann, J., Gross, W.L., Peter, H.H., 1990, A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn’s disease, Immunobiol 181: 406–13
Roth, M., Gross, V., Andus, T., Rump, J.A., Peter, H.H., Schölmerich, J., 1991, Influence of disease activity and therapy on p-ANCA reactivity of sera from repeatedly tested patients with ulcerative colitis (UC), Eur J Gastroenterol Hepatol 3 (Suppl 1): 250A
Shanahan, F., Duerr, R., Rotter, J., Yang, H., Sutherland, L., McElree, C., Landers, C., Targan, S., 1991, Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity, Gastroenterology 100: 614 A.
Calkins, B.M., Lillienfeld, A.M., Garland, C.F., Mendeloff, A.I., 1984, Trends in incidence rates of ulcerative colitis and Crohn’s disease, Dig DisSci. 29: 913–20
Truelove, S.C., Witts, L.J., 1955, Cortisone in ulcerative colitis. Final report on atherapeutic trial, BrJ Med. 2: 1041–8
Wiik, A., 1989, Delineation of a standard procedure for indirect immunofluorescence detection of ANCA, APMIS97 (Suppl 1 ): 12–13
Shanahan, F., Landers, C., Duerr, R., Targan, S.R., 1991, Neutrophil autoantibodies as disease markers for ulcerative colitis, Immunol Res. 10: 479–484
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© 1993 Springer Science+Business Media New York
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Reumaux, D., Colombel, JF., Delecourt, L., Noël, LH., Cortot, A., Duthilleul, P. (1993). Anti-Neutrophil Cytoplasmic Auto-Antibodies (ANCA) in Patients with Ulcerative Colitis (UC): Influence of Disease Activity and Familial Study. In: Gross, W.L. (eds) ANCA-Associated Vasculitides. Advances in Experimental Medicine and Biology, vol 336. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9182-2_93
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DOI: https://doi.org/10.1007/978-1-4757-9182-2_93
Publisher Name: Springer, Boston, MA
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