Implications of c-ANCA Testing for the Classification of Wegener’s Granulomatosis: Performance of Different Detection Systems

  • Ulrich Specks
  • Henry A. Homburger
  • Richard A. DeRemee
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)


The clinical spectrum of seventy-six consecutive c-ANCA positive patients is described and its relation to clinical classification schemes for Wegener’s granulomatosis (WG) is investigated. c-ANCA detection by immunofluorescence (IF) is compared to detection by two different ELISA systems.


Alveolar Hemorrhage ELISA System Necrotizing Vasculitis Nasolacrimal Duct Obstruction Lymphomatoid Granulomatosis 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Ulrich Specks
    • 1
  • Henry A. Homburger
    • 2
  • Richard A. DeRemee
    • 1
  1. 1.Division of Thoracic Disease Department of Internal MedicineMayo ClinicRochesterUSA
  2. 2.Department of Laboratory MedicineMayo ClinicRochesterUSA

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