Alpha-1-Antitrypsin, CRP and Interleukin-6 in ANCA-positive Vasculitis

  • Carola Grönhagen-Riska
  • Anna-Maija Teppo
  • Eero Honkanen
  • Risto Ikäheimo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

Alfa-1-antitrypsin (a-1-AT), C-reactive protein (CRP) and interleukin-6 (IL-6) serum levels were measured during different phases of anti-neutrophil cytoplasmic antibody (ANCA) -positive vasculitis. Correlation between ANCA and these variables was observed. Both a-1-AT and CRP fluctuations indicated changes in activity that could not always be detected by ANCA. On the other hand, these acute phase proteins were also less specific. IL-6 was not as sensitive as CRP and a-1-AT, a clearly increased mean value was observed only in patients with high ANCA titers.

Keywords

Acute Phase Protein Antineutrophil Cytoplasmic Antibody Vasculitic Activity Positive ANCA ANCA Titer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Carola Grönhagen-Riska
    • 1
  • Anna-Maija Teppo
    • 1
  • Eero Honkanen
    • 1
  • Risto Ikäheimo
    • 1
  1. 1.Division of Nephrology, IV Department of MedicineUniversity of HelsinkiHelsinkiFinland

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