ANCA in Ocular Inflammatory Disorders

  • B. Nölle
  • H. Coners
  • G. Duncker
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

400 patients presenting with active inflammation of the conjunctiva, sclera, orbita, uvea or retina were cANCA negative during active disease, however, pANCA were found in 15%. Another group of 100 patients suffering from Wegener’s granulomatosis (WG) showed in 72 cases one or multiple ocular inflammatory symptoms. They were frequently cANCA-positive. Contrary to some other reports dealing with ocular inflammation, we find a high specificity of cANCA for Wegener’s granulomatosis and, therefore, recommend cANCA-testing in all ocular inflammatory disorders, which may be difficult to differentiate from a manifestation of WG.

Keywords

Juvenile Rheumatoid Arthritis Anterior Uveitis Ocular Inflammation Retinal Vasculitis Uveitis Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • B. Nölle
    • 1
  • H. Coners
    • 1
  • G. Duncker
    • 1
  1. 1.Clinic for OphthalmologyUniversity of KielKiel 1Germany

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