Summary
Antimyeloperoxidase (MPO) antibodies are frequently encountered in patients with vasculitis. Using a competitive inhibition ELISA test and immunoblotting, we suggest that anti-MPO antibodies might represent a heterogenous group of auto-antibodies directed against different conformational epitopes of MPO molecule.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cameron, J.S., 1991, New horizons in renal vasculitis, Klin Wochenschr 69: 536–551.
Croker, B.P., Lee, T., and Gunnells, J.C., 1987, Clinical and pathologic features of polyarteritis nodosa and its renal-limited variant, Hum Pathol 18: 38–44.
Jennette, J.C., and Falk, R.J., 1990, Antineutrophil cytoplasmic autoantibodies and associated diseases: a review, Am J Kidney Dis 6: 517–529.
Wilkowski, M.J., Velosa, J.A., Holley, K.E., Offord, K.P., Chu, C., Torres, V.E., McCarthy, J.T., Donadio, J.V., and Wagoner R.D., 1989, Risk factors in idiopathic renal vasculitis and glomerulonephritis, Kidney Int 36: 1133–1141.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer Science+Business Media New York
About this chapter
Cite this chapter
Tadros, M., Pozzi, C., Radice, A., Sinico, R.A., D’Amico, G. (1993). Characterization of Anti-Myeloperoxidase Antibodies in Vasculitis. In: Gross, W.L. (eds) ANCA-Associated Vasculitides. Advances in Experimental Medicine and Biology, vol 336. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9182-2_44
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9182-2_44
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9184-6
Online ISBN: 978-1-4757-9182-2
eBook Packages: Springer Book Archive