Perinuclear Antineutrophil Cytoplasmic Antibodies (P-ANCA): Clinical Significance and Relation to Antibodies Against Myeloid Lysosomal Enzymes

  • Jan Willem Cohen Tervaert
  • A. H. Leontine Mulder
  • Cees G. M. Kallenberg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 336)

Summary

In a prospective study of 27 months duration p-ANCA were found in 120 patients. 35% of these patients had vasculitis and/or glomerulonephritis. 28% of the p-ANCA positive sera reacted with myeloid lysosomal enzymes.

Keywords

Systemic Lupus Erythematosus Ulcerative Colitis Primary Sclerosing Cholangitis Churg Strauss Syndrome Crescentic Glomerulonephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Jan Willem Cohen Tervaert
    • 1
  • A. H. Leontine Mulder
    • 1
  • Cees G. M. Kallenberg
    • 1
  1. 1.Department of Clinical ImmunologyUniversity Hospital GroningenThe Netherlands

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