Aluminum Neurotoxicity and Alzheimer’s Disease

  • Sakae Yumoto
  • Shigeo Kakimi
  • Yoshiaki Ogawa
  • Hisao Nagai
  • Mineo Imamura
  • Koichi Kobayashi
Part of the Advances in Behavioral Biology book series (ABBI, volume 44)


High aluminum concentrations have been demonstrated in the brains of patients with Alzheimer’s disease (senile dementia).1–4 Epidemiological studies have also reported that increased aluminum concentration in drinking water increases the incidence of Alzheimer’s disease.5 Based on these results, a theory that aluminum is the cause of Alzheimer’s disease has been postulated.1–5


Inclusion Body Nerve Cell Silver Powder Axodendritic Synapse Postsynaptic Structure 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Sakae Yumoto
    • 1
  • Shigeo Kakimi
    • 2
  • Yoshiaki Ogawa
    • 3
  • Hisao Nagai
    • 4
  • Mineo Imamura
    • 5
  • Koichi Kobayashi
    • 6
  1. 1.Department of AnatomyFaculty of Medicine University of TokyoBunkyo-ku, Tokyo 113Japan
  2. 2.Department of AnatomyFaculty of Medicine, Nihon UniversityItabashi-ku, Tokyo 173Japan
  3. 3.Department of AnatomySchool of Veterinary Medicine, Azabu UniversitySagamiharaKanagawa 229Japan
  4. 4.College of Humanities and SciencesNihon UniversitySetagaya-ku, Tokyo 156Japan
  5. 5.Institute for Nuclear StudyUniversity of TokyoTanashi, Tokyo 188Japan
  6. 6.Research Center for Nuclear Science and TechnologyUniversity of TokyoBunkyo-ku, Tokyo 113Japan

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