Immunomodulation by Growth Hormone in Humans

  • Robert Rapaport
Part of the Hans Selye Symposia on Neuroendocrinology and Stress book series (HSSN, volume 3)

Abstract

The role of growth hormone in the establishment and maintenance of the immune system of animals has been well documented. Beginning with the demonstration of involution of the thymus gland following hypophysectomy,1 many studies have shown diminished immune functions in hypophysectomized animals that were reversible by growth hormone administration.2–8 Growth hormone has also been reported to stimulate DNA synthesis and c-myc proto-oncogene expression9 as well as superoxide anion production10,11 in hypophysectomized rats.

Keywords

Growth Hormone Growth Hormone Deficiency Human Growth Hormone Growth Hormone Receptor Growth Hormone Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Robert Rapaport
    • 1
  1. 1.Department of Pediatrics, Division of Pediatric Endocrinology and MetabolismChildren’s Hospital of New Jersey UMD-New Jersey Medical SchoolNewarkUSA

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