The Cervical Sympathetic Trunk-Submandibular Gland Axis in the Regulation of Inflammatory Responses

  • Ronald Mathison
  • Joseph S. Davison
  • A. Dean Befus
Part of the Hans Selye Symposia on Neuroendocrinology and Stress book series (HSSN, volume 3)


Elaborate homeostatic mechanisms have been developed for regulating the main physiological variables of body temperature, heart rate, blood pressure, water balance and availability of nutrients. Major threats to an organism whether through a stress response or other insults such as infection (viral, fungal, bacterial) and noninfectious pathological causes (e.g. pancreatitis, ischemia, multiple trauma and tissue injury, haemorrhagic shock, immune-mediated organ dysfunction) elicit homeostatic responses in the major body systems; nervous, endocrine, immune, cardiovascular, respiratory, liver, kidneys and gastrointestinal tract.


Nerve Growth Factor Submandibular Gland Mean Arterial Blood Pressure Thyrotropin Release Hormone Superior Cervical Ganglion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Ronald Mathison
    • 1
  • Joseph S. Davison
    • 1
  • A. Dean Befus
    • 2
  1. 1.Department of Medical PhysiologyThe University of CalgaryCalgaryCanada
  2. 2.Pulmonary Research GroupThe University of AlbertaEdmontonCanada

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