Characteristics of the V̇O2 Slow Component During Heavy Exercise in Humans Aged 30 to 80 Years

  • C. Bell
  • D. H. Paterson
  • M. A. Babcock
  • D. A. Cunningham
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 450)


At the onset of moderate intensity exercise oxygen uptake (V̇O2) increases exponentially from baseline to a new steady-state value. The steady-state V̇O2is linearly related to work rate, such that: ΔV̇O2/ΔWR ≈ 10 (ml·min-1·W-1. When the exercise intensity is heavy, inducing a sustained increase in blood lactate concentration, then the attainment of steady-state may be delayed, or even prevented, and a slow component of increasing V̇O2is observed (10). Thus, during heavy exercise the AV?̇O2/ΔWR relationship is increased (ΔV̇O2/ΔWR > 10) and becomes non-linear.


Work Rate Slow Component Blood Lactate Concentration Ventilatory Threshold Muscle Fibre Type 
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  1. 1.
    Aniansson, A., G. Grimby, I. Krotkiewska, M. Krotkiewski, and A. Rundgren. Muscle strength and endurance in elderly people, with special reference to muscle morphology. In A. Asmussen and A. Jorgensen (Eds.), International Series on Biomechanics Vol. 2A, Biomechanics VI -(pp. 100–110). Amsterdam: Elsevier/North Holland Biomedical Press.Google Scholar
  2. 2.
    Aniansson, A., M. Hedberg, G.-B. Henning, and G. Grimby. Muscle morphology, enzymatic activity, and muscle strength in elderly men: A follow up study. Muscle Nerve 9: 585–591, 1986.PubMedCrossRefGoogle Scholar
  3. 3.
    Armon, Y., D.M. Cooper, R. Flores, S. Zanconato, and T.J. Barstow. Oxygen uptake dynamics during high-intensity exercise in children and adults. J. Appl. Physiol. 70: 841–848, 1991.PubMedCrossRefGoogle Scholar
  4. 4.
    Babcock, M.A., D.H. Paterson, D.A. Cunningham, and J.R. Dickinson. Exercise on-transient gas exchange kinetics are slowed as a function of age. Med. Sei. Sports Exerc. 26: 440–446, 1994.Google Scholar
  5. 5.
    Beaver, W.L., N. Lamarra, and K. Wasserman. Breath-by-breath measurement of true alveolar gas exchange. J. Appl. Physiol. 51: 1662–1675, 1981.PubMedGoogle Scholar
  6. 6.
    Casaburi, R., T.W. Storer, I. Ben-Dov, and K. Wasserman. Effect of endurance training on possible determinants of V?̇O2during heavy exercise. J. Appl. Physiol. 62: 199–207, 1987.PubMedGoogle Scholar
  7. 7.
    Cunningham, D.A., D.H. Paterson, J.J. Koval, and C.M. St. Croix. A model of oxygen transport capacity changes for independently living older men and women. Can. J. Appl. Physiol. 22: 439–453, 1997.PubMedCrossRefGoogle Scholar
  8. 8.
    Davis, J.A., M.H. Franks, B.J. Whipp, and K. Wasserman. Anaerobic threshold alterations caused by endurance training in middle-aged men. J. Appl. Physiol. 46: 1039–1046, 1979.PubMedGoogle Scholar
  9. 9.
    Keh-Evans, L., C.L. Rice, E.G. Noble, D.H. Paterson, D.A. Cunningham, and A.W. Taylor. Comparison of histochemical, biochemical and contractile properties of triceps surae of trained aged subjects. Can. J. Ageing 11: 4, 412–425, 1992.CrossRefGoogle Scholar
  10. 10.
    Paterson, D.H., and B.J. Whipp. Asymmetries of oxygen uptake at the on- and offset of heavy exercise in humans. Journal of Physiology 443: 575–586, 1991.PubMedGoogle Scholar
  11. 11.
    Poole, D.C., S.A. Ward, G.W. Gardner, and B.J. Whipp. Metabolic and respiratory profile of the upper limit for prolonged exercise in man. Ergonomics 31: 1265–1279, 1988.PubMedCrossRefGoogle Scholar
  12. 12.
    Schantz, P.G., and J. Henriksson. Enzyme levels of NADH shuttle systems: measurements in isolated muscle fibres from humans of differing physical activity. Acta Physiol Scand 129: 505–515, 1987.PubMedCrossRefGoogle Scholar
  13. 13.
    Taylor, C.R., R.H. Karas, E.R. Weibel, and H. Hoppeler. Adaptive variation in the mammalian respiratory system in relation to energetic demand. Resp. Physiol. 69: 1–127, 1987.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • C. Bell
    • 1
  • D. H. Paterson
    • 1
  • M. A. Babcock
    • 2
  • D. A. Cunningham
    • 1
    • 3
  1. 1.Centre for Activity and Ageing, School of KinesiologyThe University of Western OntarioLondonCanada
  2. 2.NeurodiagnosticsJohn D. Dingell VA Medical CenterDetroitUSA
  3. 3.Department of PhysiologyThe University of Western OntarioCanada

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