Abstract
The detection of DNA or RNA sequences in cells in interphase or metaphase can readily be achieved by in situ hybridization procedures based on the specific annealing of sequences (probes), previously labeled with appropriate reporter molecules, to their corresponding genomic DNA or RNA regions. Under special conditions, stable complexes are formed that can be visualized.
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Adinolfi, M., Crolla, J. (1994). Nonisotopic in Situ Hybridization. In: Harris, H., Hirschhorn, K. (eds) Advances in Human Genetics. Advances in Human Genetics, vol 22. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9062-7_5
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