Localisation and Cloning of Genes Involved in the Export of the A-Protein of Aeromonas salmonicida

  • Brian Noonan
  • Sonia Cavaignac
  • Trevor J. Trust
Part of the NATO ASI Series book series (NSSA, volume 252)


The paracrystalline surface protein array of Aeromonas salmonicida is composed of tetragonally arranged subunits of Mr = 50800 (Chu et al., 1991). The gene encoding the A-protein has recently been cloned (Belland and Trust, 1987) and sequenced (Chu et al., 1991), and studies on its 3 dimensional structure have been performed (Dooley et al., 1989). The A-layer is involved in the ability of A. salmonicida to produce disease in fish and it appears to protect the bacteria from the bacteriocidal effect of immune and non-immune serum (Ishiguro et al., 1981; Munn et al., 1982) as well as from phagocytic cells (Trust et al., 1983).


Cell Surface Hydrophobicity Aeromonas Salmonicida Extracellular Protein Secretion Activity A449 Cell Bacteriocidal Effect 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Brian Noonan
    • 1
  • Sonia Cavaignac
    • 1
  • Trevor J. Trust
    • 1
  1. 1.Department of Biochemistry and Microbiology and Canadian Bacterial Diseases NetworkUniversity of VictoriaVictoriaCanada

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