Nonlinear System Identification of Hippocampal Neurons

  • Berj L. Bardakjian
  • W. Neil Wright
  • Taufik A. Valiante
  • Peter L. Carlen


Although the passive electrical properties of neural membranes are well modeled by linear résistive-capacitive (RC) ladder networks, they do not account for the nonlinear current-voltage (I–V) relations which are observed in most neural cells. Typically the I–V relations of neuronal membranes are obtained using a voltage-clamp paradigm where it is, generally difficult to maintain a uniform transmembrane voltage. This chapter describes a white-noise identification scheme which identifies both the dendritic RC ladder networks and the somatic nonlinear I–V relations of hippocampal neurons.


Input Impedance Input Current Voltage Response Transmembrane Voltage Scatter Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Berj L. Bardakjian
    • 1
  • W. Neil Wright
    • 1
  • Taufik A. Valiante
    • 1
  • Peter L. Carlen
    • 1
  1. 1.Institute of Biomedical Engineering, Playfair Neuroscience Unit, Departments of Electrical and Computer Engineering, and MedicineUniversity of TorontoCanada

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