Nonlinear Modeling of Physiological Systems Using Principal Dynamic Modes

  • Vasilis Z. Marmarelis


The use of a small number of properly selected principal dynamic modes (PDM) may provide the long-sought parsimony and physiological interpretability of nonlinear models of physiological systems obtained from stimulus-response experimental data. The advocated approach makes use of a filter-bank comprised of the selected FDM’s that are feeding into a multi-input static nonlinear operator. This model form facilitates the system identification task and makes nonlinear modeling possible in certain cases previously thought intractable. Since the estimation of the PDM’s is based only on 1st-order and 2nd-order kernel measurements, and the estimation of the static nonlinearity can be practically extended to high-order systems, it is hoped that this modeling method will broaden the scope of Volterra-Wiener applications and facilitate the interpretation of the obtained results. This may promote the broader use of nonlinear models in studies of physical and physiological systems.


Elliptic System Volterra Series Volterra Kernel System Kernel Laguerre Function 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Vasilis Z. Marmarelis
    • 1
  1. 1.Departments of Biomedical and Electrical EngineeringUniversity of Southern CaliforniaUSA

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