Physiological Alternatives to the Effect Compartment Model

  • Nicholas H. G. Holford


The effect compartment provides a pharmacokinetic model for drug disposition at an effect site. It is not connected in a mass balance sense with the pharmacokinetic model used to describe drug disposition in the whole body.


Pharmacokinetic Model Pharmacodynamic Model Effect Compartment Physiological Substance Release Inhibitor 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Nicholas H. G. Holford
    • 1
  1. 1.Department of PharmacologyUniversity of AucklandNew Zealand

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