Mammalian Sperm Acrosomal Enzymes and the Acrosome Reaction

  • L. J. D. Zaneveld
  • C. J. De Jonge


The sperm acrosome is an intracellular membrane-limited organelle that surrounds the anterior portion of the nucleus. It consists of an inner acrosomal membrane that is closely associated with the nucleus and is continuous with the outer acrosomal membrane. The acrosomal matrix proper is located between the two membranes. The entire spermatozoon is covered by the plasma membrane. The acrosome has several characteristics in common with the lysosome: it contains a number of enzymes, and the internal milieu is normally acidic. Although all mammals possess an acrosome, significant size and shape variations exist.


Seminal Plasma Zona Pellucida Acrosome Reaction Sperm Head Sperm Membrane 
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© Springer Science+Business Media New York 1991

Authors and Affiliations

  • L. J. D. Zaneveld
    • 1
  • C. J. De Jonge
    • 2
  1. 1.Department of Obstetrics and Gynecology, and Department of BiochemistryRush University, Rush-Presbyterian-St. Luke’s Medical CenterChicagoUSA
  2. 2.Department of Obstetrics and GynecologyRush University, Rush-Presbyterian-St. Luke’s Medical CenterChicagoUSA

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