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Mammalian Sperm Acrosomal Enzymes and the Acrosome Reaction

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Book cover A Comparative Overview of Mammalian Fertilization

Abstract

The sperm acrosome is an intracellular membrane-limited organelle that surrounds the anterior portion of the nucleus. It consists of an inner acrosomal membrane that is closely associated with the nucleus and is continuous with the outer acrosomal membrane. The acrosomal matrix proper is located between the two membranes. The entire spermatozoon is covered by the plasma membrane. The acrosome has several characteristics in common with the lysosome: it contains a number of enzymes, and the internal milieu is normally acidic. Although all mammals possess an acrosome, significant size and shape variations exist.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, and Department of Biochemistry, Rush University, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, 60612, USA

    L. J. D. Zaneveld

  2. Department of Obstetrics and Gynecology, Rush University, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, 60612, USA

    C. J. De Jonge

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  1. L. J. D. Zaneveld
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  1. Department of Cell Biology, Baylor College of Medicine, 77030, Houston, Texas, USA

    Bonnie S. Dunbar

  2. Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill, 27599, Chapel Hill, North Carolina, USA

    Michael G. O’Rand

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Zaneveld, L.J.D., De Jonge, C.J. (1991). Mammalian Sperm Acrosomal Enzymes and the Acrosome Reaction. In: Dunbar, B.S., O’Rand, M.G. (eds) A Comparative Overview of Mammalian Fertilization. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-8982-9_4

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