Fertilization in the Guinea Pig
Since the study of guinea pig fertilization and early development began over 137 years ago (see references cited by Hunter et al., 1969), the guinea pig has been an important experimental animal for investigators trying to understand mechanisms of sperm—egg interaction that lead to fertilization. The purpose of this review is not to provide an exhaustive treatise on the subject. Rather, advantages and disadvantages of the guinea pig system are discussed with particular reference to specific areas of research that have received considerable attention. In addition, prospective areas for future investigations are highlighted.
KeywordsZona Pellucida Acrosome Reaction Apical Segment Testicular Sperm Sperm Capacitation
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- Huang, T. T. F., Hardy, D., Yanagimachi, H., Teuscher, C., Ring, K., Wild, G., and Yanagimachi, R., 1985, pH and protease control of acrosomal content stasis and release during the guinea pig sperm acrosome reaction, Biol. Reprod. 32: 451–462.Google Scholar
- Schenk, S. L., 1878, Das Sangethierei kunstlich befruchtet ausserhalb des Mutter thieves, Mitt. Embryol. Inst. K.K. Univ. Wien 1: 107–118.Google Scholar
- Sharon, N., 1975, Complex Carbohydrates, Addison-Wesley, Reading, MA, pp. 155–166.Google Scholar
- Young, W. C., 1931, A study of the function of the epididymis. III. Functional changes undergone by spermatozoa during their passage through the epididymis and vas deferens in the guinea-pig, J. Expo. Biol. 8: 151–162.Google Scholar