Concluding Remarks

  • A. Lowenthal
  • A. Mori
  • B. Marescau
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 153)

Abstract

First I would like to point out this was a multidisciplinary meeting, in which both clinicians and basic scientists participated. An improved understanding of the urea cycle was the goal of this symposium. In physiological conditions the urea cycle enables the organism to get rid of ammonia. Malfunction leads to accumulation of ammonia, ammonia containing compounds and other metabolites of the urea cycle. The urea cycle is not an isolated metabolic pathway in the organism; it connects to other pathways, such as those that allow urea metabolism, such as the transformation of ornithine in various metabolites, like proline, and of arginine in monoguanidines. For this last pathway, one remaining question is if guanidinosuccinic acid is a metabolite of urea or of arginine.

Keywords

Urea Cycle Orotic Acid Multidisciplinary Meeting Urea Synthesis Positive Screening Result 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • A. Lowenthal
    • 1
  • A. Mori
    • 2
  • B. Marescau
    • 1
  1. 1.Born-Bunge FoundationUniversitaire Instelling AntwerpenWilrijkBelgium
  2. 2.Institute for NeurobiologyOkayama University Medical SchoolOkayamaJapan

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