Treatment of Pyruvic and Lactic Acidaemia in Ophthalmoplegia Plus

  • G. Scarlato
  • M. Moggio
  • F. Fici
  • C. Cerri
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 153)


Disorders of lactate and pyruvate metabolism are a relatively common feature in a number of different diseases frequently associated with mitochondrial abnormalities in muscle, brain, liver and heart. As it is well-known, pyruvate sits at the center of any ordinary chart of intermediary metabolism. The formation of pyruvate is primarily from glucose by the process of glycolyses and its utilization is by transamination, reduction, carboxylation or oxidation processes. Therefore pyruvate and lactate metabolism are under control of several enzymatic mechanisms.


Pyruvic Acid Citric Acid Cycle Mitochondrial Myopathy Mitochondrial Abnormality Lactate Metabolism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • G. Scarlato
    • 1
  • M. Moggio
    • 1
  • F. Fici
    • 2
  • C. Cerri
    • 1
  1. 1.Clinica Neurologica IIa Universita’ di MilanoMilanoItaly
  2. 2.Istituto Lusofarmaco d’ItaliaMilanoItaly

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