Guanidino Compounds and Hemodialysis

  • Yohji Ochiai
  • Shinya Abe
  • Teruo Yamada
  • Keiichi Tada
  • Futami Kosaka
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 153)

Abstract

Despite a large number of reports that have appeared recently in regard to guanidino compounds and their role in causing uremia and aggravating renal failure, many points are still unclear. There are very few reports on guanidino compounds in acute renal failure, and those that are available have deficiencies related to the clinical assessment or etiological research. Furthermore, many of the patients admitted to the Intensive Care Unit have renal failure in a high risk situation of multiple organ failure, thus contributing to the difficulty of treatment by dialysis. The clinical picture varies, and can include those with infective foci, decreased immunological capacity, and unstable circulatory and respiratory system, abnormality of the central nervous system, and hepatic failure or disseminated intravascular coagulation. The pathophysiology of acute renal failure was investigated to elucidate the miscellaneous complicating factors by analyzing guanidino compounds in patients requiring hemodialysis.

Keywords

Acute Renal Failure Disseminate Intravascular Coagulation Uremic Toxin Hepatic Coma High Risk Situation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Ando, A., Nakata, K., Tsubakihara, Y. Tanaka, T. and Abe, Y., 1976, Guanidino Compounds as Uremic Toxin, Saishin-Igaku 31: 1695.Google Scholar
  2. Bartholomew, R. A., Calvin, E. D., Grimes, W. H., Jr., and Fish, J. S., 1957, Facts pertinent to the Etiology of Eclamptogenic Toxemia. A Summation of Previous Observations, Amer. J. Obstet. Gynec., 74: 64.Google Scholar
  3. Giovannetti, S., and Barsotti, G., 1974, Dialysis of Methylguanidine, Kidney International, 6: 177.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Yohji Ochiai
    • 1
  • Shinya Abe
    • 1
  • Teruo Yamada
    • 1
  • Keiichi Tada
    • 1
  • Futami Kosaka
    • 1
  1. 1.Department of AnesthesiologyOkayama University Hospital and Intensive Care UnitOkayama 700Japan

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